Evaluation of the Effects of Cornus mas L. Fruit Extract on Glycemic Control and Insulin Level in Type 2 Diabetic Adult Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial
Table 2
The effects of interventions on tested parameters after 6 weeks in the study subjects. The values are presented as mean ± SD.
Parameter
Cornus mas
Placebo
P value
(unit)
(between groups)
BMI (kg/m2)
End
29.06 ± 1.60
29.31 ± 2.07
0.062
Change
−0.33 ± 0.45
0.10 ± 0.45
P value
0.723
0.320
FPG (mg/dL)
End
143.30 ± 40.19
178.73 ± 38.80
0.130
Change
−14.63 ± 36.87
4.06 ± 55.39
P value
0.038
0.691
Insulin (μU/mL)
End
6.80 ± 3.20
5.27 ± 2.53
0.001
Change
1.13 ± 1.90
−0.643 ± 1.82
P value
0.003
0.064
HbA1C (%)
End
7.49 ± 0.71
7.81 ± 0.64
0.005
Change
−0.240 ± 0.429
0.023 ± 0.225
P value
0.005
0.621
2Hpp (mg/dL)
End
222.17 ± 55.17
244.83 ± 63.27
0.247
Change
−6.23 ± 46.19
13.63 ± 80.76
P value
0.466
0.363
TG (mg/dL)
End
174.70 ± 78.28
240.26 ± 147.97
0.014
Change
−23.66 ± 55.40
2.83 ± 15.71
P value
0.026
0.332
BMI: body mass index; FPG: fasting plasma glucose; 2Hpp: 2-hour postprandial glucose; TG: triglyceride.