Evaluation of the Effects of Cornus mas L. Fruit Extract on Glycemic Control and Insulin Level in Type 2 Diabetic Adult Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial

Table 2

The effects of interventions on tested parameters after 6 weeks in the study subjects. The values are presented as mean ± SD.

Parameter	Cornus mas	Placebo	P value
(unit)			(between groups)
BMI (kg/m^2)
End	29.06 ± 1.60	29.31 ± 2.07	0.062
Change	−0.33 ± 0.45	0.10 ± 0.45
P value	0.723	0.320
FPG (mg/dL)
End	143.30 ± 40.19	178.73 ± 38.80	0.130
Change	−14.63 ± 36.87	4.06 ± 55.39
P value	0.038	0.691
Insulin (μU/mL)
End	6.80 ± 3.20	5.27 ± 2.53	0.001
Change	1.13 ± 1.90	−0.643 ± 1.82
P value	0.003	0.064
HbA1C (%)
End	7.49 ± 0.71	7.81 ± 0.64	0.005
Change	−0.240 ± 0.429	0.023 ± 0.225
P value	0.005	0.621
2Hpp (mg/dL)
End	222.17 ± 55.17	244.83 ± 63.27	0.247
Change	−6.23 ± 46.19	13.63 ± 80.76
P value	0.466	0.363
TG (mg/dL)
End	174.70 ± 78.28	240.26 ± 147.97	0.014
Change	−23.66 ± 55.40	2.83 ± 15.71
P value	0.026	0.332

BMI: body mass index; FPG: fasting plasma glucose; 2Hpp: 2-hour postprandial glucose; TG: triglyceride.