Litsea japonica Extract Inhibits Aldose Reductase Activity and Hyperglycemia-Induced Lenticular Sorbitol Accumulation in db/db Mice

Table 1

Inhibition of rat lens aldose reductase by LJE.

	Concentration (μg/mL)	Inhibition (%)	IC50 value^a (μg/mL)
LJE	10	42.38 ± 3.58	13.53 ± 0.74
	12.5	47.35 ± 1.72
	15	53.64 ± 4.14
3,3-Tetramethyleneglutaric acid	3.7	31.42 ± 5.71	5.34 ± 0.89
	5.5	56.42 ± 9.60
	7.4	69.69 ± 8.15

The inhibitory effect is expressed as the mean of four experiments. IC₅₀ values were calculated from dose inhibition curves.