Research Article

Hypocholesterolemic and Antiatherosclerotic Potential of Basella alba Leaf Extract in Hypercholesterolemia-Induced Rabbits

Table 4

Levels of antioxidant enzymes in serum of rabbits from various groups.

G1G2 G3 G4 G5

SOD (U/mL)
 Baseline5.88 ± 0.175.63 ± 0.255.93 ± 0.115.72 ± 0.155.84 ± 0.12
 Week 45.98 ± 0.215.49 ± 0.345.61 ± 0.185.39 ± 0.305.33 ± 0.21
 Week 86.05 ± 0.225.35 ± 0.295.25 ± 0.254.96 ± 0.175.10 ± 0.31
 Week 126.20 ± 0.184.91 ± 0.205.04 ± 0.285.21 ± 0.735.38 ± 0.35
GPx (U/L)
 Baseline1243.73 ± 91.211211.65 ± 101.191443.10 ± 55.781313.95 ± 232.951401.20 ± 171.33
 Week 41330.85 ± 77.531198.58 ± 90.381351.83 ± 128.171277.18 ± 184.681274.78 ± 124.44
 Week 81459.45 ± 175.801055.30 ± 62.231205.00 ± 82.151079.55 ± 213.701169.20 ± 82.50
 Week 121595.35 ± 219.20885.23 ± 43.84975.53 ± 62.411241.63 ± 181.981418.5 ± 82.55

G1: normal control, G2: hypercholesterolemic control, G3: simvastatin-treated (10 mg/kg), G4: B. alba extract-treated (100 mg/kg), and G5: B. alba extract-treated (200 mg/kg). All data are presented as the mean ± SD ( for each group). One-way ANOVA was performed followed by Dunnett’s post hoc test for multiple comparisons. Within a week, values sharing the same superscript letters are not significantly different from each other ( < 0.05).