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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 751743, 12 pages
Review Article

Correlations between Phlegm Syndrome of Chinese Medicine and Coronary Angiography: A Systematic Review and Meta-Analysis

1Hunan University of Chinese Medicine, Science-Education Industrial Park, Yuelu Region, Changsha 410208, China
2The First Hospital of Hunan University of Chinese Medicine, No. 95 of Shaoshan Road, Yuhua Region, Changsha 410007, China
3No. 8 Hospital of Changsha, No. 22 of Xingsha Street, Xingsha Region, Changsha 410100, China

Received 21 August 2014; Revised 18 September 2014; Accepted 23 October 2014

Academic Editor: Ka-Fai Chung

Copyright © 2015 Qiu-Yan Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Phlegm is one of the most common patterns of coronary artery disease (CAD) in Chinese medicine. Our research was aimed at investigating the association between phlegm syndrome of CAD and coronary angiography (CAG) by meta-analysis. According to inclusion criteria, a total of 30 studies involving 5,055 CAD patients were included. The meta-analysis showed that phlegm syndrome patients were prone to multivessel disease (28 studies, OR = 1.53, 95% CI, 1.24 to 1.88, ) and higher Gensini score (2 studies, OR = 5.90, 95% CI, 1.86 to 9.94, ), but not obviously relevant to severe stenosis (≥75%) of coronary arteries (13 studies, OR = 1.20, 95% CI, 0.63 to 2.27, ). We concluded that the coronary arteries lesions of CAD patients with phlegm syndrome were more severe than those with nonphlegm syndromes. Phlegm syndrome should, therefore, be regarded as a dangerous pattern of CAD with worse prognosis.