Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 761238, 8 pages
http://dx.doi.org/10.1155/2015/761238
Research Article

Rapid Antidepressant Activity of Ethanol Extract of Gardenia jasminoides Ellis Is Associated with Upregulation of BDNF Expression in the Hippocampus

1Center for Translational Systems Biology and Neuroscience, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China
2Laboratory of Integrative Biomedicine of Brain Diseases, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China
3First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China

Received 3 February 2015; Accepted 27 February 2015

Academic Editor: David Mischoulon

Copyright © 2015 Hailou Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. C. B. Nemeroff, “The burden of severe depression: a review of diagnostic challenges and treatment alternatives,” Journal of Psychiatric Research, vol. 41, no. 3-4, pp. 189–206, 2007. View at Publisher · View at Google Scholar
  2. M. aan het Rot, K. A. Collins, and H. L. Fitterling, “Physical exercise and depression,” Mount Sinai Journal of Medicine, vol. 76, no. 2, pp. 204–214, 2009. View at Publisher · View at Google Scholar
  3. M. H. Trivedi, A. J. Rush, S. R. Wisniewski et al., “Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice,” The American Journal of Psychiatry, vol. 163, no. 1, pp. 28–40, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. R. M. Berman, A. Cappiello, A. Anand et al., “Antidepressant effects of ketamine in depressed patients,” Biological Psychiatry, vol. 47, no. 4, pp. 351–354, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. C. A. Zarate Jr., J. B. Singh, P. J. Carlson et al., “A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression,” Archives of General Psychiatry, vol. 63, no. 8, pp. 856–864, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. J. H. Krystal, “Ketamine and the potential role for rapid-acting antidepressant medications,” Swiss Medical Weekly, vol. 137, no. 15-16, pp. 215–216, 2007. View at Google Scholar
  7. A. E. Autry, M. Adachi, E. Nosyreva et al., “NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses,” Nature, vol. 475, no. 7354, pp. 91–96, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. N. Li, B. Lee, R.-J. Liu et al., “mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists,” Science, vol. 329, no. 5994, pp. 959–964, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. M. J. Niciu, I. D. Henter, D. A. Luckenbaugh, C. A. Zarate Jr., and D. S. Charney, “Glutamate receptor antagonists as fast-acting therapeutic alternatives for the treatment of depression: ketamine and other compounds,” Annual Review of Pharmacology and Toxicology, vol. 54, pp. 119–139, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. X. H. Wei, X. M. Cheng, J. S. Shen, and Z. T. Wang, “Antidepressant effect of Yueju-Wan ethanol extract and its fractions in mice models of despair,” Journal of Ethnopharmacology, vol. 117, no. 2, pp. 339–344, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. X. H. Wei, X. D. Xu, J. S. Shen, and Z. T. Wang, “Antidepressant effect of Yueju ethanol extract and its constituents in mice models of despair,” China Pharmacy, vol. 20, pp. 166–168, 2009. View at Google Scholar
  12. W. Xue, X. Zhou, N. Yi et al., “Yueju pill rapidly induces antidepressant-like effects and acutely enhances BDNF expression in mouse brain,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 184367, 9 pages, 2013. View at Publisher · View at Google Scholar
  13. D. F. Ionescu, D. A. Luckenbaugh, M. J. Niciu et al., “Effect of baseline anxious depression on initial and sustained antidepressant response to ketamine,” The Journal of Clinical Psychiatry, vol. 75, pp. e932–e938, 2014. View at Publisher · View at Google Scholar
  14. Z. Zhong-Liu and L. Yong-Hui, “Study on antidepressant effect and mechanism by Cyperus rotundus extracts,” Chinese Journal of Experimental Traditional Medical Formulae, vol. 18, pp. 191–193, 2012. View at Google Scholar
  15. J.-M. Wang, Y.-X. Ma, B. Zhang, Q.-W. Li, and Y. Cui, “Antidepressant-like effects of extracts isolated from rhizomes of Cyperus rotundus L.,” Lishizhen Medicine and Materia Medica Research, vol. 24, no. 4, pp. 779–781, 2013. View at Google Scholar
  16. W. Y. Hao, Z. Yang, Y. Z. Gao et al., “Effect of the crude extract of Cape jasmine on behavior and the hippocampal neurogenesis in mouse model of depression,” Chinese Journal of Comparative Medicine, vol. 10, pp. 11–14, 31, 84, 2009. View at Google Scholar
  17. J. Steru, R. Chermat, B. Thierry et al., “The automated tail suspension test: a computerized device which differentiates psychotropic drugs,” Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 11, no. 6, pp. 659–671, 1987. View at Google Scholar · View at Scopus
  18. S. Maeng, C. A. Zarate Jr., J. Du et al., “Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors,” Biological Psychiatry, vol. 63, no. 4, pp. 349–352, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Mingmalairak, M. Tohda, Y. Murakami, and K. Matsumoto, “Possible involvement of signal transducers and activators of transcription 3 system on depression in the model mice brain,” Biological & Pharmaceutical Bulletin, vol. 33, no. 4, pp. 636–640, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. J. H. Kim, G. H. Kim, and K. H. Hwang, “Monoamine oxidase and dopamine β-hydroxylase inhibitors from the fruits of Gardenia jasminoides,” Biomolecules & Therapeutics, vol. 20, no. 2, pp. 214–219, 2012. View at Publisher · View at Google Scholar · View at Scopus
  21. Q.-S. Wang, J.-S. Tian, Y.-L. Cui, and S. Gao, “Genipin is active via modulating monoaminergic transmission and levels of brain-derived neurotrophic factor (BDNF) in rat model of depression,” Neuroscience, vol. 275, pp. 365–373, 2014. View at Publisher · View at Google Scholar
  22. J. F. Cryan, C. Mombereau, and A. Vassout, “The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice,” Neuroscience and Biobehavioral Reviews, vol. 29, no. 4-5, pp. 571–625, 2005. View at Publisher · View at Google Scholar · View at Scopus
  23. K. Martinowich, H. Manji, and B. Lu, “New insights into BDNF function in depression and anxiety,” Nature Neuroscience, vol. 10, no. 9, pp. 1089–1093, 2007. View at Publisher · View at Google Scholar · View at Scopus
  24. N. M. Tsankova, O. Berton, W. Renthal, A. Kumar, R. L. Neve, and E. J. Nestler, “Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action,” Nature Neuroscience, vol. 9, no. 4, pp. 519–525, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. A. E. Lepack, M. Fuchikami, J. M. Dwyer, M. Banasr, and R. S. Duman, “BDNF release is required for the behavioral actions of ketamine,” The International Journal of Neuropsychopharmacology, vol. 18, no. 1, 2014. View at Publisher · View at Google Scholar
  26. H. Kuratsune, N. Umigai, R. Takeno, Y. Kajimoto, and T. Nakano, “Effect of crocetin from Gardenia Jasminoides Ellis on sleep: a pilot study,” Phytomedicine, vol. 17, no. 11, pp. 840–843, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. X. Wu, Y. Zhou, F. Yin et al., “Quality control and producing areas differentiation of Gardeniae Fructus for eight bioactive constituents by HPLC-DAD-ESI/MS,” Phytomedicine, vol. 21, no. 4, pp. 551–559, 2014. View at Publisher · View at Google Scholar · View at Scopus
  28. Y. Sun, F. Feng, and X. Yu, “Pharmacokinetics of geniposide in Zhi-Zi-Hou-Pu decoction and in different combinations of its constituent herbs,” Phytotherapy Research, vol. 26, no. 1, pp. 67–72, 2012. View at Publisher · View at Google Scholar · View at Scopus
  29. W. Tao, H. Zhang, W. Xue et al., “Optimization of supercritical fluid extraction of oil from the fruit of Gardenia jasminoides and its antidepressant activity,” Molecules, vol. 19, no. 12, pp. 19350–19360, 2014. View at Publisher · View at Google Scholar