Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 761238, 8 pages
http://dx.doi.org/10.1155/2015/761238
Research Article

Rapid Antidepressant Activity of Ethanol Extract of Gardenia jasminoides Ellis Is Associated with Upregulation of BDNF Expression in the Hippocampus

1Center for Translational Systems Biology and Neuroscience, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China
2Laboratory of Integrative Biomedicine of Brain Diseases, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China
3First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China

Received 3 February 2015; Accepted 27 February 2015

Academic Editor: David Mischoulon

Copyright © 2015 Hailou Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The effect dosage of the ethanol-extracted Yueju pill was 2.7g/kg, in which each of five constituent herbs contributed to 0.54g/kg. We tested whether each herb constituents of Yueju showed rapid antidepressant-like potent at this dosage. In tail suspension test carried out at 24 hours post a single administration of ethanol-extracted individual herbs, we found that none of them showed a significant effect(ANOVA, F(5,47)=0.148,p=0.979).

  1. Supplementary Material