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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 761565, 9 pages
Research Article

Study on TCM Syndrome Differentiation of Primary Liver Cancer Based on the Analysis of Latent Structural Model

1Changhai Hospital of Traditional Chinese Medicine, Second Military Medical University, Shanghai 200433, China
2Anhui Jing’an Hospital of Integrated Traditional Chinese and Western Medicine, Hefei 230031, China

Received 10 July 2014; Accepted 18 September 2014

Academic Editor: Zhao-Xiang Bian

Copyright © 2015 Zhan Gu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Primary liver cancer (PLC) is one of the most common malignant tumors because of its high incidence and high mortality. Traditional Chinese medicine (TCM) plays an active role in the treatment of PLC. As the most important part in the TCM system, syndrome differentiation based on the clinical manifestations from traditional four diagnostic methods has met great challenges and questions with the lack of statistical validation support. In this study, we provided evidences for TCM syndrome differentiation of PLC using the method of analysis of latent structural model from clinic data, thus providing basis for establishing TCM syndrome criteria. And also we obtain the common syndromes of PLC as well as their typical clinical manifestations, respectively.