Influence of the Alcohol Present in a Phytotherapic Tincture on Male Rat Lipid Profiles and Renal Function
Table 2
Effect of the indicated treatments on biochemical parameters in male rats.
Parameter
Control
EP
Alcohol
10-day treatment
Albumin (g⋅dL−1)
2.80 ± 0.01
2.68 ± 0.09
2.70 ± 0.07
ALT (U⋅L−1)
45.6 ± 4.08
47.0 ± 6.01
48.9 ± 5.18
AST (U⋅L−1)
79.8 ± 12.30
81.5 ± 9.25
80.0 ± 13.07
Cholesterol (mg⋅dL−1)
75.8 ± 5.32
96.3 ± 3.18
95.3 ± 2.56
Creatinine (mg⋅dL−1)
0.36 ± 0.01
0.42 ± 0.09
0.39 ± 0.03
GGT (U⋅L−1)
<10
<10
<10
Glucose (mg⋅dL−1)
72 ± 13.50
80 ± 12.80
83 ± 11.90
HDL (mg⋅dL−1)
43.8 ± 3.09
54.7 ± 3.84
47.3 ± 3.17
LDL (mg⋅dL−1)
24.6 ± 2.58
30.8 ± 4.50
21.7 ± 0.88
LDH (mg⋅dL−1)
348 ± 52.30
319 ± 48.70
352 ± 31.30
Triglycerides (mg⋅dL−1)
74.5 ± 9.87
85.3 ± 13.60
82.5 ± 10.50
Urea (mg⋅dL−1)
36.3 ± 0.99
32.3 ± 5.17
36.8 ± 1.80
Uric acid (mg⋅dL−1)
1.73 ± 0.32
0.83 ± 0.08
0.82 ± 0.04
15-day treatment
Albumin (g⋅dL−1)
2.80 ± 0.16
2.52 ± 0.07
2.62 ± 0.08
ALT (U⋅L−1)
48.0 ± 7.60
48.8 ± 3.41
51.2 ± 4.27
AST (U⋅L−1)
80.2 ± 14.00
83.7 ± 12.04
81.1 ± 11.20
Cholesterol (mg⋅dL−1)
92.3 ± 18.90
97.4 ± 3.94
95.0 ± 4.48
Creatinine (mg⋅dL−1)
0.48 ± 0.03
0.92 ± 0.10
1.04 ± 0.10
GGT (U⋅L−1)
<10
<10
<10
Glucose (mg⋅dL−1)
89 ± 12.40
93 ± 6.67
122 ± 9.40
HDL (mg⋅dL−1)
54.4 ± 6.00
55.5 ± 2.53
55.4 ± 1.66
LDL (mg⋅dL−1)
28.5 ± 1.70
28.8 ± 1.65
22.8 ± 1.31
LDH (mg⋅dL−1)
357 ± 59.60
208 ± 43.20
349 ± 59.70
Triglycerides (mg⋅dL−1)
86.0 ± 3.51
55.0 ± 7.91
87.3 ± 6.94
Urea (mg⋅dL−1)
36.3 ± 1.49
30.4 ± 2.48
32.4 ± 1.12
Uric acid (mg⋅dL−1)
1.50 ± 0.25
1.52 ± 0.12
2.00 ± 0.28
30-day treatment
Albumin (g⋅dL−1)
2.82 ± 0.02
2.66 ± 0.10
2.74 ± 0.07
ALT (U⋅L−1)
49.32 ± 10.04
47.1 ± 8.17
51.0 ± 9.13
AST (U⋅L−1)
83.0 ± 7.38
84.1 ± 9.90
85.3 ± 10.02
Cholesterol (mg⋅dL−1)
97.5 ± 0.65
90.0 ± 1.96
92.5 ± 3.43
Creatinine (mg⋅dL−1)
0.48 ± 0.02
0.70 ± 0.03
0.72 ± 0.02
GGT (U⋅L−1)
<10
<10
<10
Glucose (mg⋅dL−1)
74 ± 10.50
88 ± 10.80
90 ± 13.90
HDL (mg⋅dL−1)
56.2 ± 1.11
57.0 ± 3.70
57.0 ± 3.39
LDL (mg⋅dL−1)
26.3 ± 2.33
23.3 ± 2.73
28.8 ± 1.20
LDH (mg⋅dL−1)
322 ± 40.00
331 ± 90.70
371 ± 27.80
Triglycerides (mg⋅dL−1)
81.8 ± 5.02
56.8 ± 4.80
50.0 ± 3.91
Urea (mg⋅dL−1)
36.0 ± 1.38
34.6 ± 1.33
38.4 ± 1.29
Uric acid (mg⋅dL−1)
1.26 ± 0.87
0.74 ± 0.07
0.84 ± 0.09
ALT, alanine aminotransferase; AST, aspartate aminotransferase; EP, Específico-Pessôa phytotherapic tincture; GGT, gamma glutamyltransferase; HDL, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol, LDH, lactate dehydrogenase. ALT, AST, and GGT values represent the mean ± SEM of 3 animals. The other parameters represent the mean ± SEM of 5 animals. for the comparison between the EP and alcohol groups. , for the comparison with the relevant control group. The values represent Dunnett’s test.
