Research Article

Protective Effects of N-Acetyl-L-Cysteine in Human Oligodendrocyte Progenitor Cells and Restoration of Motor Function in Neonatal Rats with Hypoxic-Ischemic Encephalopathy

Figure 1

Effects of NAC and vitamin C on KCN cytotoxicity in F3.Olig2 human oligodendrocyte progenitor cells. (a) Cytotoxicity of KCN in MTT assay. F3.olig2 cells were with various concentrations (●: 0.5 mM, ▼: 1 mM, ■: 2.5 mM, ◆: 5 mM, and ▲: 7.5 mM) of KCN for 18 h. (b, c) F3.Olig2 cells were treated with KCN (5 mM) alone or in combination with NAC (b) or vitamin C (c) and assayed after 18 h incubation. Values with different superscript letters represent a significant difference, .