Protective Effects of N-Acetyl-L-Cysteine in Human Oligodendrocyte Progenitor Cells and Restoration of Motor Function in Neonatal Rats with Hypoxic-Ischemic Encephalopathy
Recovery of motor functions of HI rats by NAC. Rats were subjected to hypoxic-ischemic (HI) surgery at postnatal day (PND) 7, and behavioral functions in cylinder test (a–c), locomotor activity (d–f), and rotarod performance (g–i) were assessed at PND 20 (a, d, and g), 30 (b, e, and h), and 40 (c, f, and i). White: normal animals, black: HI alone, and gray: HI + NAC. Values with different superscript letters represent a significant difference, .