Protective Effects of N-Acetyl-L-Cysteine in Human Oligodendrocyte Progenitor Cells and Restoration of Motor Function in Neonatal Rats with Hypoxic-Ischemic Encephalopathy

Table 1

Statistical analysis of the apoptosis-related molecules from Figures 2 and 3.

Treatment (mM)	Annexin V positivity (%)	Bcl2 (relative to GAPDH)	Bad (relative to GAPDH)	p-ERK (relative to GAPDH)
Vehicle	3.6 ± 2.7^a	0.28 ± 0.13^a	0.001 ± 0.001^a	0.097 ± 0.015^a
KCN (5.0)	56.8 ± 4.8^b	0.11 ± 0.06^b	0.312 ± 0.124^b	0.065 ± 0.011^b
+vitamin C (0.15)	98.6 ± 7.4^c	0.21 ± 0.11^ab	0.282 ± 0.152^b	0.068 ± 0.082^ab
+NAC (0.5)	42.7 ± 3.4^d	0.37 ± 0.14^ac	0.521 ± 0.206^b	0.124 ± 0.113^a
+NAC (1.0)	32.3 ± 5.1^df	0.68 ± 0.20^d	0.341 ± 0.093^b	0.156 ± 0.108^c
+NAC (2.5)	26.1 ± 2.8^e	0.91 ± 0.26^d	0.238 ± 0.062^b	0.202 ± 0.077^c
+NAC (5.0)	31.3 ± 4.2^ef	0.82 ± 0.22^d	0.110 ± 0.046^c	0.235 ± 0.086^c

Values () in the same column with different superscript letters represent a significant difference, P < 0.05.