PMC-12, a Prescription of Traditional Korean Medicine, Improves Amyloid -Induced Cognitive Deficits through Modulation of Neuroinflammation

Figure 1

Effects of PMC-12 on spatial learning and memory in -injected mice based on the Morris water maze test. Changes in escape latency (a) and swimming distance (b) to reach the platform in mice treated with distilled water (Veh) or PMC-12 (100 or 500 mg/kg/day, orally for 3 weeks) at 3 weeks after injection. injection significantly increased escape latency time and swimming distance ( versus control, two-way ANOVA), which was reversed by PMC-12 (100 and 500 mg/kg, and versus vehicle, resp., two-way ANOVA). ^** versus control (Con); ^# and ^## versus vehicle (Veh). Data shown are the mean ± SEM from nine separate experiments.

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