Antithrombotic Effects of Five Organic Extracts of Bangladeshi Plants In Vitro and Mechanisms in In Silico Models

Table 3

In vitro clot lysis activity of Ocimum tenuiflorum, Andrographis paniculata, Adhatoda vasica, Leea macrophylla, and Litsea glutinosa.

Herbs/drugs	Fractions	% of clot lysis (mean ± SD)	value (two-tailed); when compared to; negative control (water)
Negative control (water)	Methanol	8.89 ± 2.22	—
Positive control (streptokinase)	Methanol	71.14 ± 6.91
Ocimum tenuiflorum	Methanol	26.08 ± 5.12
Andrographis paniculata	Methanol	35.74 ± 6.76
Adhatoda vasica	Methanol	22.86 ± 3.61
Leea macrophylla	Methanol	47.47 ± 6.65
Litsea glutinosa	Methanol	27.25 ± 3.97

Values are mean ± SD ( = 20); ^*, ^**, Dunnett test as compared to control (positive and negative). Statistical representation of the effective clot lysis percentage by herbal preparations, positive thrombolytic control (streptokinase), and negative control (sterile distilled water) processed by paired -test analysis (Dunnett test).