Hypoglycemic Effect of Ethanol and Ethyl Acetate Extract of Phellinus baumii Fruiting Body in Streptozotocin-Induced Diabetic Mice

Table 4

Effect of P.  baumii on morphology of islet.

Group	Dose; (mg/kg)	Animal number^a; (piece)	Islet number; (piece/pcs)	Islet area; (µm^2/pcs)
Control	—	10	1.25 ± 0.27	8561 ± 1734
Model	—	9	0.13 ± 0.07^##	1633 ± 359^##
AcOEt; extract	100	9	0.31 ± 0.18	2162 ± 707
	200	10	0.43 ± 0.25	2349 ± 1057
	400	9	0.41 ± 0.22	2989 ± 1231
EtOH; extract	100	10	0.23 ± 0.16	2025 ± 1235
	200	9	0.30 ± 0.18	2643 ± 1511
	400	10	0.33 ± 0.18	2781 ± 1548
Metformin	160	10	0.35 ± 0.21	2593 ± 1234

versus normal control group; , versus model control group.
^aMice number of each group at 14th day.