Research Article

Progressive Muscle Relaxation Improves Anxiety and Depression of Pulmonary Arterial Hypertension Patients

Table 2

Baseline clinical characteristics of patients.

Control
()
PMR
()

PAH diagnosis (%)Idiopathic26 (44.1)27 (49.1)0.87
Congenital heart disease19 (32.2)16 (29.1)
Connective tissue disease14 (23.7)12 (21.8)

PAH therapy (%)Monotherapy 34 (57.6)30 (54.5)0.89
Dual therapy20 (33.9)21 (38.2)
Triple therapy5 (8.5)4 (7.3)
Oxygen therapy23 (39.0)24 (43.6)

PAH-targeted medicationET receptor antagonists36 (61.0)35 (63.6)0.98
Phosphodiesterase-5 inhibitors37 (62.7)36 (65.5)
Prostanoids10 (16.9)8 (14.5)
Calcium channel blockers9 (15.3)9 (16.4)

Course of disease (years)7.9 ± 5.27.5 ± 5.40.65

6MWD (meters) 374.9 ± 136.2368.2 ± 143.50.87

WHO functional class (%)I 3 (5.1)2 (3.6)0.92
II24 (40.7)22 (40.0)
III 32 (54.2)31 (56.4)

Hypertension (%)41 (69.5)37 (67.3)0.84

COPD (%)18 (30.5)19 (34.5)0.69

Coronary heart disease (%)15 (25.4)12 (21.8)0.67

Type II diabetes mellitus (%)11 (18.6)9 (16.4)0.81

Sleep apnea (%)9 (15.3)10 (18.2)0.80

Note: for continuous variables, all values were expressed as mean ± SD and Student’s -tests were performed to compare means between the groups. For categorical variables, all values were expressed as (%) and comparisons were performed with Chi-square tests. PAH: pulmonary arterial hypertension; 6MWD: 6-minute walk distance; WHO: World Health Organization; ET: endothelin; COPD: chronic obstructive pulmonary disease.