Transcriptional Regulation of CYP3A4/2B6/2C9 Mediated via Nuclear Receptor PXR by Helicid and Its Metabolites

Figure 6

PCR amplified CYP3A4, CYP2B6, and CYP2C9 promoter proximal and distal regulatory sequences (M is DNA Marker DL2,000, 1, 2 are CYP3A4 promoter proximal and distal bands, 3, 4 are CYP2B6 promoter proximal and distal bands, and 5, 6 are CYP2C9 promoter proximal and distal bands).

(a)

(b)