Antihypertensive Effect of the GaMiSamHwangSaSimTang in Spontaneous Hypertensive Rats

Figure 4

Effect of HVC1 on endothelium-intact aortic rings preincubated with indomethacin or atropine. Graph showing relaxation responses induced by HVC1 in endothelium-intact spontaneous hypertensive rat aortic rings that had been precontracted with phenylephrine (PE, 1 μM) in Krebs-Henseleit solution in the presence or absence of indomethacin (10 μM) or atropine (1 μM). The relaxant effects of HVC1 on isolated spontaneous hypertensive rat aortic rings were calculated as a percentage of the contraction in response to PE. Values are expressed as mean ± SEM ().