Adenosine A2A Receptors Mediate Anti-Inflammatory Effects of Electroacupuncture on Synovitis in Mice with Collagen-Induced Arthritis

Figure 2

The CIA model, clinical symptoms and time course. (a) No clinical signs of CIA were observed in Sham-control mice. (b) CIA developed rapidly in mice immunized with CII, with clinical signs such as periarticular edema and erythema.

(a) Sham-control

(b) CIA-control

(c) (%) Incidence of CIA