Adenosine A2A Receptors Mediate Anti-Inflammatory Effects of Electroacupuncture on Synovitis in Mice with Collagen-Induced Arthritis

Figure 3

Radiography of hind paws with CIA. Radiographic assessment of bone damage in the tibiotarsal joints of mice with CIA. There is no evidence of bone resorption in joints of mice in the Sham-control group (a, f). Hind paws from CIA-control mice showed bone resorption (b, f). CIA-EA mice showed less bone resorption than CIA-control mice (b, c). There was no significant decrease of the radiographic score of CIA-EA-SCH58261 mice (d, f) and CIA-SCH58261 mice (e, f) compared to CIA-control mice. Values are means ± SEM of 10 animals for each group. versus Sham-control. ^Δ versus CIA-control. ^# versus CIA-EA.

(a) Sham-control

(b) CIA-control

(c) CIA-EA

(d) CIA-EA-SCH58261

(e) CIA-SCH58261

(f)