Antibacterial and Antiproliferative Activities of Plumericin, an Iridoid Isolated from Momordica charantia Vine

Table 6

Cell cycle determination of NB4 and K562 cells showed that, at 48 h, the apoptosis significantly occurred when compared with the control group. Moreover, G2/M arrest was also detected in K562 cells.

NB4	Concentration (g/mL)	Apoptosis	G0	S	G2M
48 hrs	0	4.44	36.54	46.43	11.91
	2.5 (0.5ED50)	40.13	40	15.92	3.19
	5 (ED50)	73.46	16.22	8.96	0.89
K562	Concentration (g/mL)	Apoptosis	G0	S	G2M
48 hrs	0	4.15	16.01	58.39	18.5
	2.5 (0.5ED50)	5.27	11.98	44.25	31.72
	5 (ED50)	9.08	22.94	41.98	23.1