The Consumption of Bicarbonate-Rich Mineral Water Improves Glycemic Control

Figure 2

Comparisons of blood metabolites between TW and BMW consumption periods. (a) Relative concentrations of each metabolite in blood were transformed to -score by subjects and shown as heat maps using blue-black-yellow scheme. Gray color indicates that the metabolites were not detected in the sample. A total of 152 metabolites were arranged in increasing order of value that was calculated by Wilcoxon signed-rank test between TW and BMW consumption periods. (b) Mean relative concentrations of each metabolite (-score) of weeks 1 and 3 (TW) and weeks 2 and 4 (BMW) were shown in dot plots overlaid on box plots in the same manner as in Figure 1(a). Only 19 metabolites that their concentrations were significantly increased (upper 9 metabolites) or decreased (lower 10 metabolites) after BMW consumption (shown in upper block of panel (a)) were demonstrated. (c) Relative concentrations of 3-hydroxybutyrate in blood were shown in dot plots overlaid on box plots in the same manner as in Figure 1(a). NS: not significant; ; .

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