[Retracted] Effect of Rat Medicated Serum Containing Zuo Gui Wan and/or You Gui Wan on the Differentiation of Stem Cells Derived from Human First Trimester Umbilical Cord into Oocyte-Like Cells In Vitro

Figure 2

Effect of rat medicated serums on morphological changes of inducing stem cells into oocyte-like cells. (a), (b), and (c) show representative images of stem cells treated with the rat medicated serums containing common ingredients of ZGW/YGW, YGW, and ZGW, respectively. On day 7, some subpopulations of the cells appeared to be morphologically distinct from the cells on day 0, which resembled PGC (green arrows). On day 24, OLCs developed and were surrounded by smaller cells that showed resemblance to follicular structures (red arrows). Higher magnification images of OLCs are also presented to show that they are in pachytene. (d) shows representative images of stem cells treated with normal rat serum. No significant morphological changes were found during the entire period of 24 days. Scale bar is set to 100 μm.