Review Article

External Application of Traditional Chinese Medicine for Venous Ulcers: A Systematic Review and Meta-Analysis

Table 2

Treatments used in the included studies.

StudyConventional therapy of experimental group/control groupTopical treatment of control groupExternal application of experimental groupSuppliers of the externally applied TCM
Surgical treatmentEndovenous surgical proceduresCompression therapyPharmacological treatment

Cao et al., 2005 [20]NANANRAntibiotics and nutritional supportVaseline ointmentSheXiangZhenZhu ointmentThe 306th Hospital of Chinese People’s Liberation Army

Di, 2009 [14]NANACompression bandages or hosieryNRGentamicinQiXing powderChengdu University of TCM

Fang et al., 2012 [26]VLSNACompression bandages or hosieryAntibiotics if necessaryAlginate dressingHuangDou pasteHospital of Laiwu Iron and Steel Group Limited Company (Chinese Patent Number: ZL 200710115133.0)

Feng, 2009 [9]NANANRNRErythromycin ointmentKuiYangPing ointmentLiaoning University of TCM

Huang et al., 2009 [19]NASEPSNRNRNRShengJi ointmentThe Second Affiliated Hospital of Heilongjiang University of TCM

Jia and Li, 2011 [10]NANACompression bandagesNR0.1% ethacridine lactateShengJiYuYang powderTCM Hospital of Hebei Province

Jia, 2012 [15]VLSNANRAntibiotics and nutritional supportVaseline ointment + gentamicinMoist exposed burn ointment (MEBO)Shantou Meibao Pharmaceutical Co., Ltd.

Li and Zhang, 2013 [11]NAEVLTCompression bandagesAntibiotics and aspirinNRShengJiYuHong ointmentTCM Hospital of HanDan city

Peng, 2014 [16]NANACompression bandagesDanhong injection; elastic bandage0.1% ethacridine lactate0.1% ethacridine lactate + Chinese herbal powderTCM Hospital of Hebei Province

Wang, 2013 [17]NANAIPC + Compression bandagesSalvia miltiorrhiza and ligustrazine injectionethacridine lactateChinese herbs external washingTCM Hospital of Hebei Province

Xu, 2009 [21]NANANRAntibioticsNRShengJiYuHong ointmentTCM Hospital of Jiangsu Province

Xu, 2012 [22]NANANRNREthacridine lactateChinese herbs external washing + HongYou ointmentShuguang Hospital, Shanghai University of TCM

Zhang et al., 2007 [23]NANACompression hosieryAntibiotics if necessary and nutritional supportVaseline ointmentFuFangSanHuang ointmentTCM Hospital of Shijiazhuang City

Zhang et al., 2008 [24]VLSNACompression hosieryNRNRChinese herbs external washingPeople’s Hospital of Yunnan Chuxiong

Zhang et al., 2008 [18]NAEVLT Compression bandagesNRSensitive antibioticsHongYou ointmentShuguang Hospital, Shanghai University of TCM

Zhang, 2013 [25]NANANRNRMetronidazoleKuiYang oilDongzhimen Hospital, Beijing University of Chinese Medicine

NA, not available; NR, no report; TCM, traditional Chinese medicine; VLS, venous ligation and stripping; SEPS, subfascial endoscopic perforator vein surgery; EVLT, endovenous laser treatment; IPC, intermittent pneumatic compression.