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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 839697, 9 pages
http://dx.doi.org/10.1155/2015/839697
Research Article

Immunoregulation on Mice of Low Immunity and Effects on Five Kinds of Human Cancer Cells of Panax japonicus Polysaccharide

1Third Xiangya Hospital, Central South University, Changsha 410013, China
2Changsha University, Changsha 410022, China
3School of Pharmaceutical Science, Central South University, Changsha 410013, China
4The Central Hospital of Taian, Taian 271000, China
5Maternal and Child Health Hospital, Liuyang 410300, China

Received 25 December 2014; Revised 9 April 2015; Accepted 16 April 2015

Academic Editor: Jairo Kennup Bastos

Copyright © 2015 Zhang Jie et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Z. X. Du, Pharmaceutical Botany, People’s Medical Publishing House, 2009.
  2. P. Wang, “Study on the anti-inflammatory and analgesic effect of Panax japonicus,” Journal of Sichuan of Traditional Chinese Medicine, vol. 25, no. 12, pp. 17–19, 2007. View at Google Scholar
  3. D. J. Wen, C. L. Zhang, G. D. Chen, X. G. Dong, and B. J. Xiao, “Study on the analgesic effects of total Panax japonicus Saponins,” Lishizhen Medicine and Materia Medica Research, vol. 19, no. 8, pp. 1983–1984, 2008. View at Google Scholar
  4. F. Borrelli and A. A. Izzo, “The plant kingdom as a source of anti-ulcer remedies,” Phytotherapy Research, vol. 14, no. 8, pp. 581–591, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. J. Yuan, “The protective of panax japonicus saponins on myocardial ischemia reperfusion injury in dogs,” Journal of Medicine and Pharmacy of Chinese Minorities, vol. 3, pp. 48–50, 2008. View at Google Scholar
  6. D. C. Xiang, “Influence of Panax japonicus on rats which suffered from limb ischemia reperfusion,” Chinese Journal of Clinical Rational Drug Use, vol. 3, no. 11, pp. 1–2, 2010. View at Google Scholar
  7. J. Min and M. Z. Ao, “Effect of total saponins of Panax japonicus on immunological function,” Lishizhen Medicine and Materia Medica Research, vol. 18, no. 11, pp. 2784–2785, 2007. View at Google Scholar
  8. D. Yuan, Y. Y. Dun, and C. C. Zhang, “Inhibitory effect of total saponins of Panax japonicus on the proliferation of synoviocytes in collagen-induced arthritis rats,” Lishizhen Medicine and Materia Medica Research, vol. 19, no. 8, pp. 1882–1883, 2008. View at Google Scholar
  9. J. Min, “Anti-inflammatory effect of total saponins of Panax japonicus,” Journal of Xiangning University, vol. 23, no. 6, pp. 464–467, 2009. View at Google Scholar
  10. Z. F. Wang, Q. L. Tan, and H. Zhang, “Experimental studies on the mechanism of compound Japanese Ginseng pill in treatment of rheumatoid arthritis,” Lishizhen Medicine and Materia Medica Research, vol. 20, no. 7, pp. 1611–1613, 2009. View at Google Scholar
  11. L. N. Qian, P. Chen, X. L. Li, and Y. Y. Xiao, “Study on the antifatigue function of total saponins from Panax japonicas,” Chinese Journal of Hospital Pharmacy, vol. 28, no. 15, pp. 1238–1240, 2008. View at Google Scholar
  12. H. Liu, “Experimental research on the antifatigue effect of Panax Japonicus,” Journal of Hubei Institute for Nationalities (Medical Edition), vol. 18, no. 3, pp. 4–6, 2001. View at Google Scholar
  13. G. F. Ni and Zhejiang, “Experimental study on anti-tumor activity of different extracts from Panax japonicus in vitro,” Journal of Traditional Chinese Medicine, vol. 42, no. 4, pp. 230–231, 2007. View at Google Scholar
  14. D. Yuan, R. Zuo, and C. H. Zhang, “Effects of total saponins of Panax japonicas on human leukemic HL-60 cells,” Journal of Chinese Integrative Medicine, vol. 5, no. 5, pp. 570–572, 2007. View at Google Scholar
  15. Y. L. N. Ou, D. W. Xiang, X. Wu, and D. X. Xiang, “The research progress for chemical components and pharmacological activities of Panax japonicas,” Chinese Herbal Medicines, vol. 41, no. 6, pp. 1023–1027, 2010. View at Google Scholar
  16. K. Ohtani, S. Hatono, K. Mizutani, R. Kasai, and O. Tanaka, “Reticuloendothelial system-activating polysaccharides from rhizomes of Panax japonicus. I. Tochibanan-A and -B,” Chemical and Pharmaceutical Bulletin, vol. 37, no. 10, pp. 2587–2591, 1989. View at Publisher · View at Google Scholar · View at Scopus
  17. C.-C. Zhang, H.-X. Zhao, M.-J. Jiang et al., “Effects of polysaccharides isolated from Panax japonicus on immunosuppression mice,” Journal of Chinese Medicinal Materials, vol. 34, no. 1, pp. 91–94, 2011. View at Google Scholar · View at Scopus
  18. J. Zhang, C. Y. Li, J. P. Li, J. Pan, and D. X. Xiang, “Determination of polysaccharide in rhizome of Panax japonicus by anthrone sulfuric acid and phenol sulfuric method,” Central South Pharmacy, vol. 10, no. 6, pp. 421–424, 2012. View at Google Scholar
  19. Q. Chen, Research Methods in Pharmacology of Chinese Materia Medica, People's Medical Publishing House, 2011.
  20. R. Wang, P. Chen, F. Jia, J. Tang, and F. Ma, “Optimization of polysaccharides from Panax japonicus C.A. Meyer by RSM and its anti-oxidant activity,” International Journal of Biological Macromolecules, vol. 50, no. 2, pp. 331–336, 2012. View at Publisher · View at Google Scholar · View at Scopus
  21. B. Xu, Study on the Composition and Activity of Polysaccharides from Panax japonicus C.A. Meyer, Wuhan Polytechnic University, Wuhan, China, 2009.
  22. X. Yang, R. F. Wang, S. P. Zhang et al., “Polysaccharides from Panax japonicus C.A. Meyer and their antioxidant activities,” Carbohydrate Polymers, vol. 101, no. 1, pp. 386–391, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. S. Salva, G. Marranzino, J. Villena, G. Agüero, and S. Alvarez, “Probiotic Lactobacillus strains protect against myelosuppression and immunosuppression in cyclophosphamide-treated mice,” International Immunopharmacology, vol. 22, no. 1, pp. 209–221, 2014. View at Publisher · View at Google Scholar
  24. A. Zong, H. Cao, and F. Wang, “Anticancer polysaccharides from natural resources: a review of recent research,” Carbohydrate Polymers, vol. 90, no. 4, pp. 1395–1410, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. R. Wang, P. Chen, F. Jia, J. Tang, F. Ma, and B. Xu, “Characterization and antioxidant activities of polysaccharides from Panax japonicus C.A. Meyer,” Carbohydrate Polymers, vol. 88, no. 4, pp. 1402–1406, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. H. Zhang, H. F. Wang, Y. Liu et al., “The haematopoietic effect of Panax japonicus on blood deficiency model mice,” Journal of Ethnopharmacology, vol. 154, no. 3, pp. 818–824, 2014. View at Google Scholar