Research Article

Relationship of Genetic Polymorphisms of the Chemokine, CCL5, and Its Receptor, CCR5, with Coronary Artery Disease in Taiwan

Table 1

Demographics and clinical characteristics of patients in non-CAD () and CAD groups ()1,2.

Non-CAD ()CAD () value

Gender
 Male 108 (67.1%) 240 (74.5%) 0.085
Age (y)65.79 ± 12.4166.69 ± 11.000.929
Height (cm) 161.28 ± 8.92161.85 ± 8.49 0.499
Weight (kg) 65.99 ± 13.2166.91 ± 12.62 0.461
BMI (kg/m2) 25.26 ± 3.9225.52 ± 4.50 0.525
AF positive (%) 41 (25.5%)30 (9.3%)<0.001
CAD risk ≥3 (%)76 (47.2%) 190 (59.0%) 0.014
Age >65 year (%)90 (55.9%) 174 (54.0%) 0.698
Family history (%)34 (21.1%) 59 (18.3%) 0.463
Hypertension (%)95 (59.0%) 242 (75.2%) <0.001
Diabetes mellitus (%)56 (34.8%) 139 (43.2%) 0.077
Active smoker (%)64 (39.8%) 146 (45.3%) 0.243
Cholesterol >200 (%)66 (41.8%) 129 (40.3%) 0.760
ASA use in the past 7 days (%)39 (24.4%) 117 (38.2%) 0.003
Recent (<24 h) sever angina (%)90 (55.9%) 227 (70.7%) 0.001
Cardiac markers elevation (%)66 (41.0%) 194 (60.2%) <0.001
Stroke21 (13.8%) 34 (11.0%) 0.374
CHF52 (32.9%) 67 (21.3%) 0.006
SBP (mmHg)130.56 ± 18.64132.86 ± 21.13 0.246
DBP (mmHg)77.61 ± 14.3179.28 ± 15.62 0.260

1Data were presented as number (percentage) with chi-square test/Fisher exact test.
2Mean ± SD with independent two-sample -test.