Research Article
Relationship of Genetic Polymorphisms of the Chemokine, CCL5, and Its Receptor, CCR5, with Coronary Artery Disease in Taiwan
Table 4
Genotyping frequencies and association of demographics features between two alleles of CCL5-403 for CAD group1.
| | | CCL5-403 | CCL5-403 | OR (95% CI) | value | | CC () | CT + TT () |
| | Male | 110 (74.3%) | 130 (74.7%) | 1.021 (0.617–1.688) | 0.936 | | AF positive (%) | 15 (10.1%) | 15 (8.6%) | 0.836 (0.394–1.774) | 0.641 | | CAD risk ≥3 (%) | 85 (57.4%) | 105 (60.3%) | 1.128 (0.722–1.761) | 0.596 | | Age >65 year (%) | 72 (48.6%) | 102 (58.6%) | 1.495 (0.962–2.325) | 0.074 | | Family history (%) | 29 (19.6%) | 30 (17.2%) | 0.855 (0.486–1.504) | 0.856 | | Hypertension (%) | 114 (77.0%) | 128 (73.6%) | 0.830 (0.498–1.382) | 0.473 | | Diabetes mellitus (%) | 69 (46.6%) | 70 (40.2%) | 0.771 (0.495–1.200) | 0.248 | | Active smoker (%) | 68 (45.9%) | 78 (44.8%) | 0.956 (0.616–1.485) | 0.841 | | Cholesterol >200 (%) | 58 (39.2%) | 71 (41.3%) | 1.091 (0.697–1.708) | 0.704 | | ASA use in the past 7 days (%) | 62 (43.7%) | 55 (33.5%) | 0.651 (0.409–1.035) | 0.069 | | Recent (<24 h) sever angina (%) | 103 (69.6%) | 124 (71.7%) | 1.106 (0.683–1.790) | 0.683 | | Cardiac markers elevation (%) | 90 (60.8%) | 104 (59.8%) | 0.957 (0.612–1.499) | 0.849 | | Stroke | 16 (11.4%) | 18 (10.6%) | 0.918 (0.449–1.874) | 0.814 | | CHF | 30 (21.1%) | 37 (21.4%) | 1.016 (0.590–1.747) | 0.955 |
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1Data were presented as number (percentage) with chi-square test/Fisher exact test.
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