Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Fig 1

Research Article

Evaluation of the Inhibitory Effects of Bavachinin and Bavachin on Human Monoamine Oxidases A and B

Figure 1

Bavachinin (BNN) and bavachin (BVN) inhibitory efficacy on recombinant human monoamine oxidases (hMAOs) compared to Psoralea corylifolia ethanolic extract (PCSEE) and standard MAO-B inhibitor selegiline (DEP) at 8.5 μg/mL. BNN structure (4′-hydroxy-7-methoxy-6-(3-methyl-2-butenyl) flavanone, 7-O-methylbavachin, mw = 338.4) (i) is a BVN analog with the methyl group at C7-OMe position substituting the hydrogen (ii). BNN and BVN differently affected hMAO-B (a) and hMAO-A (b). Data points were presented as the mean ± SEM, for at least . The significance of difference between each control versus treatments for each data set was determined using one-way ANOVA followed by Dunnett’s multiple comparisons test. ; .

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.