Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Fig 2

Research Article

Evaluation of the Inhibitory Effects of Bavachinin and Bavachin on Human Monoamine Oxidases A and B

Figure 2

BNN inhibitory potency on recombinant human monoamine oxidases isozymes (hMAO-A and hMAO-B) compared to PCSEE. BNN (a) and PCSEE (b) hMAO-B inhibition is more selective than hMAO-A isoform inhibition. BNN shows close hMAO-B inhibition potency to PCSEE but with higher selectivity to inhibit B than PCSEE. Arbitrary Light Units (ALU) were measured at 25°C. Data points and IC50 values were represented by the mean ± SEM, at least. IC50 values were calculated from two separate experiments. Significance of difference between every two data sets was determined using two-way ANOVA followed by Sidak’s multiple comparisons test. .

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