Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus acutissima Cortex

<div>Representative TLC-image showing inhibition of rat liver microsomal 5α-reductase in testosterone metabolism by BK treatment. Testosterone (T.) was incubated at a final concentration of 3.5 μmol/L for 30 min in the presence or absence of rat liver microsomes (40 μg/mL) and the cofactors. Bokusoku (BK) was added at 30 μg/mL before starting the reaction. The androgens were extracted with ethyl acetate after the incubation and analyzed by TLC. All androgen standards were applied at 0.1 μg/μL/spot. DHT: dihydrotestosterone, A. diol: 5α-androstane-3α,17β-diol.</div>

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Figure 1

Figure 1: Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus acutissima Cortex

Figure 1 | Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus acutissima Cortex 