Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus acutissima Cortex

Table 1

Quantification of constituents in an extract of BK, from cortex of Quercus acutissima.

Compound category	Subcategory	Name	Molecular weight	Amount (mg/g BK)
With gallate group	Gallotannin	Tetragalloyl glucose	788.55	0.767
	Gallotannin	Pentagalloyl glucose	940.68	3.71
	Gallotannin	Hamamelitannin	484.36	0.928
	Ellagitannin	Eugeniin	938.66	4.74
	Ellagitannin	1-Desgalloyl eugeniin	786.54	2.65
	Ellagitannin	Casuarinin	936.64	0.154
	Ellagitannin	Castalagin	934.63	5.91
	Ellagitannin	Stenophyllanin C	1056.14	1.33
	Flavonoid	(−)-Epicatechin gallate	442.37	0.238
	Flavonoid	(−)-Epigallocatechin gallate	458.40	0.0603
		Gallic acid	170.12	2.89
		Methyl gallate	184.15	0.113
Without gallate group	Coumarin	Fraxin	370.31	0.183
	Flavonoid	(+)-Catechin	290.27	10.7
	Flavonoid	(±)-Gallocatechin	306.27	1.69
	Flavonoid	Chrysin	254.24	^†BQL
	Flavonoid	(+)-Taxifolin	304.25	0.0636
	Flavonoid	Luteolin	286.24	0.00366
	Flavonoid	Quercetin	302.20	0.00856
	Flavonoid	Quercitrin	448.38	0.00142
	Flavonoid	Genistein	270.24	0.000234

Methanol/water extracts of dried BK (Lot No. 2131093010) were analyzed by LC-MS/MS.
Previously reported to exist in the cortex of Quercus acutissima.
^†Amount of chrysin was below the quantification limit (BQL). The limit of quantification of chrysin is 0.000800 mg/g.