Antitumor Activities of Ethyl Acetate Extracts from Selaginella doederleinii Hieron In Vitro and In Vivo and Its Possible Mechanism

Table 3

Antitumor effects of SD extracts against tumor growth on H-22 tumor-bearing mice.

		Tumor weight (g)	Tumor growth inhibition (%)	Spleen index (mg/10 g)	Thymus index (mg/10 g)
H22	Control	1.46 ± 0.30		5.62 ± 0.83	2.02 ± 0.42
	16 g/kg	0.62 ± 0.27^**	57.7	4.96 ± 0.72	1.64 ± 0.24^*
	8 g/kg	0.88 ± 0.28^*	39.8	5.30 ± 1.02	1.79 ± 0.38
	4 g/kg	1.12 ± 0.40	23.3	5.55 ± 0.95	1.90 ± 0.32
	5-Fu	0.60 ± 0.15^**	58.9	4.76 ± 0.72^*	1.42 ± 0.2^**

Values represent mean ± SE. < 0.05 compared to the control group; < 0.01 compared to the control group.