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Study ID |
Study type | Sample size (T/C, male/female) |
Age (yr, T/C) |
Ischemic or hemorrhagic | Intervention |
Duration |
Area of eye acupuncture intervention |
Prick depth |
Outcomes |
Eye acupuncture intervention | Control intervention |
|
Wang et al. (2008) [9] | RCT | T: 60 (32/28) C: 60 (29/31) | T: 66 (42~70) C: 64 (41~70) | Ischemic | () Eye acupuncture () Basic treatment | Basic treatment () Shuxuening injection (extract of Ginkgo) () Citicoline Injection () low-dose aspirin | 14 days | Major acupoints: upper jiao, lower jiao Minor acupoints: liver, kidney, spleen, and heart | NA | CSS; FIB |
|
Zhou et al. (2011) [10] | RCT | T: 60 (46/16) C: 60 (42/18) | NA | Ischemic | () Eye acupuncture () Basic treatment | Basic treatment () Sodium Ozagrel injection () Citicoline injection () Low-dose aspirin | 15 days | Major acupoints: upper jiao, lower jiao Minor acupoints: liver, kidney, spleen, and heart | 2 mm along the cavity orbital | NDS; ET; CGRP |
|
Liu (2010) [11] | Q-RCT | T: 28 C: 28 | NA | Ischemic | () Eye acupuncture () Buyang Huanwu Decoction | Buyang Huanwu decoction | 3 weeks | Major acupoints: upper jiao, lower jiao, spleen, and heart | NA | CSS |
|
Pang (2006) [12] | RCT | T: 34 C: 34 | T: (40~70) C: (40~70) | Ischemic and hemorrhagic | () Eye acupuncture () Rehabilitation training () Basic treatment: medicine was not available | () Rehabilitation training () Basic treatment: medicine was not available | >38 days | Major acupoints: upper jiao, lower jiao Minor acupoints: liver, kidney, and heart | 9~10.5 mm in orbit | ADL |
|
Cui (2009) [13] | RCT | T: 8 (5/3) C: 10 (6/4) | T: 51.31 ± 13.25 (40~75) C: 51.59 ± 12.89 (40~75) | Ischemic | () Eye acupuncture () Basic treatment | Basic treatment () Sodium Ozagrel injection () Citicoline injection () Low-dose Aspirin | 2 weeks | Major acupoints: upper jiao, lower jiao Minor acupoints: liver, kidney, heart, spleen, and large intestine | 3 mm along the cavity orbital | CSS; ET; CGRP |
|
Li (2010) [14] | RCT | T: 23 (12/11) C: 25 (13/12) | T: 52.29 ± 14.89 (40~75) C: 52.46 ± 13.35 (40~75) | Ischemic | () Eye acupuncture () Basic treatment | Basic treatment () Sodium Ozagrel injection () Citicoline injection () Low-dose dose aspirin | 2 weeks | Major acupoints: upper jiao, lower jiao Minor acupoints: liver, kidney, heart, spleen, and large intestine | 2 mm along the cavity orbital | CSS; ET; CGRP |
|
Wang et al. (2007) [15] | RCT | T: 45 (24/21) C: 45 (26/19) | T: 63.24 (40~70) C: 64.98 (43~70) | Ischemic | () Eye acupuncture () Basic treatment | Basic treatment () Shuxuening injection () Citicoline injection () Low-dose aspirin | 14 days | Main eye acupoints: upper jiao, lower jiao Minor acupoints: liver, kidney, heart, spleen, and stomach | NA | CSS; CRP |
|
Li and Wang (2009) [16] | RCT | T: 50 C: 50 | T: (42~75) C: (42~75) | Ischemic | () Eye acupuncture () Basic treatment: medicine was not available | Basic treatment: medicine was not available | 2 weeks | Major acupoints: upper jiao | 7.5 mm in orbit | WST |
|
Chen et al. (2007) [17] | RCT | T: 40 (24/16) C: 40 (22/18) | T: 68.1 ± 8.2 (40~80) C: 67.3 ± 11.1 (40~80) | Ischemic | () Eye acupuncture () Rehabilitation training based on the Bobath (3) Basic treatment | () Rehabilitation training based on the Bobath () Basic treatment (a) t-PA (b) Aspirin (c) Mannitol injection | 3 months | Major acupoints: upper jiao, lower jiao. Minor acupoints: liver, gallbladder, kidney, heart, spleen, and middle jiao | NA | SSS; ADL; FMA |
|
Li (2009) [18] | RCT | T: 25 C: 25 | T: (50~75) C: (50~75) | Ischemic | () Eye acupuncture () Basic treatment: medicine was not available | Basic treatment: medicine was not available | 2 weeks | Major acupoints: upper jiao, kidney, and spleen | 7.5 mm in orbit | MMSE |
|
Xi (2011) [19] | Q-RCT | T: 30 (16/14) C: 30 (18/12) | T: (35~75) C: (35~75) | Ischemic and hemorrhagic | () Eye acupuncture () Basic treatment: medicine was not available () Rehabilitation training: methods were not available | () Basic treatment: medicine was not available () Rehabilitation training: methods were not available | 7 days | Major acupoints: lower jiao, lung, and spleen | NA | First defecation time; constipation symptoms evaluation |
|
Jiang (2009) [20] | RCT | T: 30 C: 30 | T: (40~70) C: (40~70) | Ischemic and hemorrhagic | () Eye acupuncture () Rehabilitation training | Rehabilitation training | 48 days | Major acupoints: upper jiao, lower jiao, kidney, and liver | 2 mm along the cavity orbital | CSS |
|
Ren and Lin (2005) [21] | Q-RCT | T: 30 (21/9) C: 28 (20/8) | T: 54 (32~78) C: 53 (37~83) | Ischemic and hemorrhagic | () Eye acupuncture () Basic treatment | Basic treatment () 20% mannitol () Cerebrolysin () Huatuo Zaizao pill () Hemorrghagic: PAMBA Nimodipine Nifedipine () Ischemic: Low molecular dextran ATP Cytochrome C for injection Dicoumarin Nimodipine Aspirin | 30 days | Major acupoints: upper jiao, lower jiao Minor acupoints: liver, gallbladder, kidney, and heart | 2 mm along the cavity orbital | Treatment efficiency |
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Gao (2012) [22] | RCT | T: 30 (18/12) C: 30 (20/10) | NA | Ischemic | () Eye acupuncture () Basic treatment | Basic treatment () Aspirin or Clopidogrel Other medicines were not available | 14 days | Major acupoints: liver, gallbladder, kidney, and heart.Minor acupoints: upper jiao, lower jiao, heart, spleen, stomach, large intestine, and bladder | 2 mm along the cavity orbital | ADL; CSS |
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Huang (2013) [23] | RCT | T: 80 (43/37) C: 76 (40/36) | T: 61.10 ± 10.12 (40~76) C: 55.72 ± 9.02 (40~76) | Ischemic and hemorrhagic | () Eye acupuncture () Neurostan | Neurostan | 8 weeks | Major acupoints: liver, middle jiao, heart Minor acupoints: kidney, spleen, and gallbladder | 2 mm along the cavity orbital | HAMD |
|
Xu et al. (2006) [24] | RCT | T: 34 (18/16) C: 26 (16/10) | T: 62.5 ± 17.5 C: 64.2 ± 7.7 | Ischemic | Eye acupuncture | Basic treatment: the medicine might be Xingding injection, compound danshen injection, and Deproteinized calf blood injection | 22 days | Major acupoints: upper jiao, lower jiao Minor acupoints: liver, kidney, and heart | NA | ET |
|
Dong (2009) [25] | RCT | T: 38 (20/18) C: 34 (18/16) | T: 63.2 ± 12.5 C: 65.1 ± 8.6 | Ischemic | Eye acupuncture | Basic treatment: the medicine might be Deproteinized calf blood injection, Shuxuening injection (extract of Ginkgo), Sanqi Panax Notoginseng injection | 7 days | Major acupoints: upper Jiao, lower Jiao. Minor acupoints: liver, kidney, and heart | NA | VEGF |
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