Rikkunshito Ameliorates Cancer Cachexia Partly through Elevation of Glucarate in Plasma

Figure 2

RKT treatment had a greater effect on plasma metabolites in tumor-bearing rats than in control rats. Volcano plots mapped by mean value of RKT/vehicle at 180 min after treatment versus −   value of t-test of RKT versus vehicle in tumor-bearing rats (a) and control rats (b). Red squares represent the metabolites which meet the criteria ( value < 0.01, fold change > 1.5 or <0.67).

(a)

(b)