Flos Puerariae Extract Ameliorates Cognitive Impairment in Streptozotocin-Induced Diabetic Mice

Figure 4

Effect of FPE on MDA formation, SOD, CAT, GSH-Px, and AChE activities in cerebral cortex and hippocampus of experimental diabetic mice. (a) FPE-treated diabetic mice significantly inhibited MDA level both in cerebral cortex and hippocampus of experimental diabetic mice. (b)–(d) Administration with FPE enhanced SOD, CAT and GSH-Px activity in cerebral cortex of experimental diabetic mice. (e) Treatment with FPE dose-dependently reversed AChE activity in cerebral cortex of experimental diabetic mice. LFPE: low dose, 50 mg/kg; MFPE: medium dose, 100 mg/kg; HFPE: high dose, 200 mg/kg. Data are means ± S.E.M. –15. versus control group; versus control group; ^# versus DM group; ^## versus DM group.

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