Evaluation of Sedative and Hypnotic Activity of Ethanolic Extract of Scoparia dulcis Linn.

Table 5

Effect of EESD on thiopental sodium-induced sleeping time.

Treatment	Dose (mg/kg)	Responses
		Onset of sleeping	Sleeping duration
Control	0.1 mL/mouse	7.81 ± 0.47	88.80 ± 4.91
Diazepam	1	5.74 ± 0.26^*	177.60 ± 2.44^*
EESD	50	7.18 ± 0.23	107.60 ± 8.08
EESD	100	6.41 ± 0.37^*	130.40 ± 7.69^*
EESD	200	5.93 ± 0.27^*	145.20 ± 6.76^*

Values are presented as the Mean ± SEM (). EESD = ethanolic extract of Scoparia dulcis; compared with the control group (one-way ANOVA followed by Dunnett’s test).