Table 2: Changes in primary and secondary outcomes and other physical activities during the 24 weeks of intervention (ITT analyses)a.

VariablesComparisonMean change from baseline (95% CI)Between-group difference (95% CI)
Tai Chi ( = 106)Control ( = 107)Tai Chi versus control valueb

CES-D depression score3 mths versus baseline−3.6 (−4.7 to −2.6)−1.1 (−1.8 to −0.4)−3.0 (−4.3 to −1.8)<0.001
6 mths versus baseline−5.0 (−6.2 to −3.8)−1.0 (−1.9 to −0.2)−4.5 (−5.9 to −3.0)<0.001

DASS depression score12 wks versus baseline−5.9 (−7.6 to −4.1)−0.9 (−2.4 to 0.5)−5.6 (−7.7 to −3.5)<0.001
24 wks versus baseline−7.2 (−9.0 to −5.3)−0.6 (−2.2 to 1.0)−7.2 (−9.4 to −5.0)<0.001

DASS anxiety score12 wks versus baseline−1.8 (−3.0 to −0.6)0.4 (−0.7 to 1.4)−2.3 (−3.8 to −0.8)0.003
24 wks versus baseline−2.2 (−3.3 to −1.1)0.4 (−0.6 to 1.4)−2.7 (−4.1 to −1.2)<0.001

DASS stress score12 wks versus baseline−4.0 (−5.6 to −2.4)−0.6 (−2.0 to 0.7)−3.6 (−5.5 to −1.6)<0.001
24 wks versus baseline−4.4 (−6.2 to −2.7)−1.1 (−2.3 to 0.2)−3.6 (−5.5 to −1.6)<0.001

Leg strength (number of stands in 30 s)12 wks versus baseline1.5 (1.0 to 2.1)0.5 (0.0 to 0.9)1.1 (0.4 to 1.8)0.001
24 wks versus baseline2.0 (1.3 to 2.7)0.5 (0.0 to 1.0)1.6 (0.7 to 2.4)<0.001

Waist circumference (cm)12 wks versus baseline−1.4 (−2.2 to −0.7)−1.4 (−2.2 to −0.7)−0.0 (−1.0 to 1.0)0.97
24 wks versus baseline−1.2 (−2.1 to −0.3)−1.8 (−2.7 to −0.9)0.6 (−0.6 to 1.9)0.32

Body mass index (kg/m2)12 wks versus baseline−0.1 (−0.2 to 0.1)0.0 (−0.2 to 0.2)−0.1 (−0.3 to 0.2)0.54
24 wks versus baseline−0.1 (−0.3 to 0.1)0.1 (−0.1 to 0.4)−0.2 (−0.5 to 0.1)0.17

Fasting blood glucose (mmol/L)12 wks versus baseline0.1 (−0.1 to 0.4)−0.0 (−0.2 to 0.2)0.1 (−0.2 to 0.4)0.43
24 wks versus baseline0.1 (−0.1 to 0.3)0.1 (−0.1 to 0.3)−0.1 (−0.3 to 0.2)0.62

Systolic blood pressure (mmHg)12 wks versus baseline1.2 (−0.3 to 2.7)0.5 (−1.6 to 2.5)0.5 (−1.7 to 2.7)0.64
24 wks versus baseline1.0 (−0.3 to 2.4)0.4 (−1.5 to 2.3)0.4 (−1.7 to 2.5)0.71

Diastolic blood pressure (mmHg)12 wks versus baseline0.7 (−0.3 to 1.6)−0.2 (−1.3 to 0.8)0.9 (−0.3 to 2.1)0.15
24 wks versus baseline0.1 (−0.8 to 1.0)−0.1 (−1.0 to 0.9)0.2 (−1.0 to 1.4)0.77

Triglyceride (mmol/L)12 wks versus baseline−0.06 (−0.24 to 0.12)0.03 (−0.07 to 0.13)0.01 (−0.15 to 0.16)0.94
24 wks versus baseline−0.12 (−0.37 to 0.13)−0.01 (−0.11 to 0.09)−0.01 (−0.19 to 0.16)0.88

HDL-cholesterol (mmol/L)12 wks versus baseline0.0 (0.0 to 0.1)0.0 (−0.0 to 0.1)0.0 (−0.0 to 0.1)0.65
24 wks versus baseline0.1 (0.0 to 0.1)0.1 (0.0 to 0.1)−0.0 (−0.0 to 0.0)0.93

Other physical activities (hours)Total in first 12 wksMean = 25.6Mean = 47.3−21.9 (−36.7 to −7.2)0.004
Total in second 12 wksMean = 24.4Mean = 50.5−26.1 (−46.6 to −5.5)0.013

Values were calculated with intention-to-treat analyses.
bP values were calculated with generalized estimating equations analyses after adjustment for baseline.
ITT = intention-to-treat analyses.
CI = confidence interval.
CES-D = Center for Epidemiologic Studies Depression Scale 10.
DASS = Depression Anxiety Stress Scale 21.