Neutrophilic Lung Inflammation Suppressed by Picroside II Is Associated with TGF-β Signaling

Figure 4

H&E staining of lung sections from LPS-induced ALI mice. ALI was induced in mice (/group). Mice received an intratracheal spraying of LPS to the lung (C57BL/6; (b), (c), and (d)) and subsequently two different amounts of PIC II [0.5 mg/kg body weight (c) or 1 mg/kg body weight (d)] or PBS (a). Representatives of at least five different areas of a lung (magnification 100x) are shown.

(a)

(b)

(c)

(d)