Neutrophilic Lung Inflammation Suppressed by Picroside II Is Associated with TGF-β Signaling

Figure 5

PIC II suppresses neutrophilic lung inflammation in ALI mice. Bronchoalveolar lavage (BAL) was performed with ALI mice (/group) treated with or without PIC II. Total cells in the lavage fluid (a) and neutrophils and macrophages (b) were counted. Data represent the mean ± SEM of 5 mice. and were less than 0.05 and 0.001, respectively, compared with the LPS only. (c) MPO assay was performed with the lung tissues of the mice. Values are expressed as the mean ± SEM of 5 mice. Similar experiment was performed three times. and were less than 0.05, compared with the only LPS treated.

(a)

(b)

(c)