Evaluation of a Topical Herbal Agent for the Promotion of Bone Healing

Table 3

Change of biochemical markers in serum after drill-hole bone defects had been created.

	BALP (U/L)			Dpd (nmol/L)
	Control	CDNR	value	Control	CDNR	value
Day −1	3.582 ± 1.207	3.473 ± 1.391	0.882	3.665 ± 1.421	2.862 ± 0.577	0.229
Day 14	4.887 ± 1.610	4.606 ± 1.649	0.762	2.964 ± 1.118	2.614 ± 0.710	0.532
Day 28	5.909 ± 2.235	5.120 ± 2.458	0.557	2.761 ± 1.657	2.303 ± 0.624	0.540
Day 42	4.991 ± 1.605	5.283 ± 2.153	0.785	2.791 ± 1.586	1.891 ± 0.411	0.208

There was no significant difference in the serum biochemical markers between Control and CDNR at each time point. Day −1: blood was collected prior to the drill-hole bone defect creation; BALP: bone-specific alkaline phosphatase; Dpd: deoxypyridinoline. Data are expressed as mean ± standard deviation.