Apple Peel Supplemented Diet Reduces Parameters of Metabolic Syndrome and Atherogenic Progression in ApoE−/− Mice
Table 2
Biochemical parameters and initial and final weight and weight gain of the different groups of CF-1 mice subjected to different diets.
Biochemical component
ND
FD
FD + HAP
FD + SDAP
FD + DAP
Total cholesterol (mg/dL)
102 ± 5
164 ± 30∗
101 ± 9&
103 ± 3&
112 ± 7&
HDL cholesterol (mg/dL)
56 ± 7
66 ± 13
53 ± 6
50 ± 4
61 ± 9
Total/HDL cholesterol (mg/dL)
1.8 ± 0.1
1.5 ± 0.1
2 ± 0.1
1.8 ± 0.3
1.9 ± 0.1
Triglyceridemia (mg/dL)
106 ± 8
171 ± 5∗∗∗
81 ± 9∗&&&
74 ± 8∗&&&
80 ± 7∗&&&
Glycemia (mg/dL)
311 ± 10
343 ± 4
134 ± 30∗∗∗&&&
278 ± 28
294 ± 28
GOT (UI/L)
166 ± 48
144 ± 21
94 ± 19
116 ± 16
94 ± 33
Uric acid (mg/dL)
1.8 ± 0.2
2.7 ± 1.0
0.8 ± 0.6&
1.2 ± 0.4
1.2 ± 0.6
Initial weight (g)
37.3 ± 1.3
38.0 ± 0.9
37.0 ± 1.4
36.4 ± 1.3
36.5 ± 1.1
Final weight (g)
44.3 ± 0.9
45.1 ± 1.1
45.2 ± 1.3
43.3 ± 1.5
43.2 ± 1.5
Gain (g)
6.9 ± 0.12
7.5 ± 0.35∗∗
6.2 ± 0.55∗&&&
6.0 ± 0.58∗&&&
6.7 ± 0.60∗
ND, normal diet; FD, fat diet; HAP, healthy apple peel; SDAP, sun damaged apple peel; DAP, dehydrated apple peel. HDL: high density lipoprotein and GOT: glutamic-oxaloacetic transaminase. The results are expressed as the ±SD average. Statistical significance: ∗ < 0.05, ∗∗ < 0.01, and ∗∗∗ < 0.001 are compared with the ND group and & < 0.05 and &&& < 0.001 are compared with the FD group.
