Apple Peel Supplemented Diet Reduces Parameters of Metabolic Syndrome and Atherogenic Progression in ApoE−/− Mice

Table 3

Biochemical parameters and initial and final weight in different groups of ApoE−/− mice subjected to different diets.

Biochemical component	WT	ApoE−/−; ND	ApoE−/−; FD	ApoE−/−; FD + HAP
Total cholesterol (mg/dL)	86 ± 9	317 ± 67	533 ± 154^∗∗	515 ± 132^∗∗
Triglyceridemia (mg/dL)	55 ± 4	141 ± 16	185 ± 42	146 ± 55
Glycemia (mg/dL)	157 ± 44	161 ± 58	324 ± 128^∗	231 ± 107
Initial weight (g)	29.1 ± 1.8	32.5 ± 1.9	34.0 ± 2.2	34.1 ± 1.6
Final weight (g)	32.1 ± 1.8	35.1 ± 1.2	43.4 ± 4.3^∗∗∗	40.1 ± 1.9^∗∗,&

ND, normal diet; FD, fat diet; HAP, healthy apple peel.
The results are expressed as the ±SD average.
Statistical significance: ^∗∗ < 0.01, ^∗∗∗ < 0.001 final weight compared with the ND group and ^& < 0.05 compared with the FD group.
Statistical significance ^∗ < 0.05.