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Evidence-Based Complementary and Alternative Medicine
Volume 2015 (2015), Article ID 926565, 10 pages
Research Article

Therapeutic Touch Has Significant Effects on Mouse Breast Cancer Metastasis and Immune Responses but Not Primary Tumor Size

1Department of Surgery, University of Connecticut Health Center, Farmington, CT 06030, USA
2Department of Immunology, University of Connecticut Health Center, Farmington, CT 06030, USA
3Hartford Healthcare, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102-5037, USA
4Department of Reconstructive Sciences, University of Connecticut Health Center, Farmington, CT 06030, USA

Received 10 March 2015; Accepted 4 May 2015

Academic Editor: Waris Qidwai

Copyright © 2015 Gloria Gronowicz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Evidence-based integrative medicine therapies have been introduced to promote wellness and offset side-effects from cancer treatment. Energy medicine is an integrative medicine technique using the human biofield to promote well-being. The biofield therapy chosen for study was Therapeutic Touch (TT). Breast cancer tumors were initiated in mice by injection of metastatic 66cl4 mammary carcinoma cells. The control group received only vehicle. TT or mock treatments were performed twice a week for 10 minutes. Two experienced TT practitioners alternated treatments. At 26 days, metastasis to popliteal lymph nodes was determined by clonogenic assay. Changes in immune function were measured by analysis of serum cytokines and by fluorescent activated cells sorting (FACS) of immune cells from the spleen and lymph nodes. No significant differences were found in body weight gain or tumor size. Metastasis was significantly reduced in the TT-treated mice compared to mock-treated mice. Cancer significantly elevated eleven cytokines. TT significantly reduced IL-1-a, MIG, IL-1b, and MIP-2 to control/vehicle levels. FACS demonstrated that TT significantly reduced specific splenic lymphocyte subsets and macrophages were significantly elevated with cancer. Human biofield therapy had no significant effect on primary tumor but produced significant effects on metastasis and immune responses in a mouse breast cancer model.