The Protective Effect of Lacidipine on Myocardial Remodeling Is Mediated by the Suppression in Expression of GPR78 and CHOP in Rats

Table 1

Effects of lacidipine on heart rate and blood pressure.

Group	Heart rate (bpm)	MAP (mmHg)
Normal blank group	335.25 ± 26.2	112.57 ± 10.42
SHR control group	357.48 ± 29.5^*	140.35 ± 11.73^**
Captopril positive control group	342.48 ± 27.2^#	127.12 ± 8.73^##
Lacidipine 1.44 mg/kg group	351.18 ± 28.1	134.86 ± 9.55
Lacidipine 0.72 mg/kg group	341.32 ± 26.9^#	128.65 ± 8.67^##
Lacidipine 0.36 mg/kg group	346.48 ± 27.7	132.41 ± 9.23^#

MAP: mean arterial pressure; ^* < 0.05, ^** < 0.01 compared with normal blank group; ^# < 0.05, ^## < 0.01 compared with SHR control group.