Anticancer and Anti-Inflammatory Activities of a Standardized Dichloromethane Extract from Piper umbellatum L. Leaves

Table 1

Concentration (µg/mL) of Piper umbellatum SDE and doxorubicin (DOXO) required for total growth inhibition of cell lines (TGI values^a).

Cell lines	Total growth inhibition (µg/mL)
	DOXO	SDE
UACC-62	0.9	6.8
U251	1.6	8.2
MCF-7	0.2	9.3
NCI-ADR/RES	1.9	14.9
786-0	1.1	9.1
NCI-H460	1.9	11.5
PC-3	1.9	8.2
OVCAR-3	1.2	8.3
HT-29	6.2	207.3
HaCat	29.1	144.6

TGI values were determined by nonlinear regression analysis using ORIGIN 8.0 (OriginLab Corporation). Experiments were conducted in triplicate and results are representative of three different experiments.