Anticancer and Anti-Inflammatory Activities of a Standardized Dichloromethane Extract from Piper umbellatum L. Leaves

Table 2

Cell blood count and organs weight (mean ± SEM) from animals treated (oral route) with vehicle and P. umbellatum SDE (100, 200, and 400 mg/kg) during 21 days.

Organs	Vehicle	100	200	400
Liver (g)	0.048 ± 0.001	0.045 ± 0.0010	0.046 ± 0.0029	0.051 ± 0.0009
Kidneys (g)	0.012 ± 0.0001	0.012 ± 0.0002	0.013 ± 0.0002	0.012 ± 0.0003
Spleen (g)	0.004 ± 0.0002	0.005 ± 0.0002	0.005 ± 0.0007	0.004 ± 0.0001
Cell blood count
WBC (10^6/μL)	4.4 ± 0.3	3.3 ± 0.3	3.7 ± 0.7	4.7 ± 0.6
Haemoglobin (g/dL)	14.2 ± 0.3	14.2 ± 0.2	13.9 ± 0.5	13.9 ± 0.2
Platelet (10^3/μL)	1169 ± 44.5	1278 ± 28.9	1403 ± 76.3	1388 ± 61.9

Vehicle = PBS + Tween 80 0.3%, pH 7.0.