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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 957031, 14 pages
http://dx.doi.org/10.1155/2015/957031
Research Article

Flavonoid Fraction of Orange and Bergamot Juices Protect Human Lung Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Stress

1Department of Drug Sciences and Products for Health, University of Messina, Viale Annunziata, 98168 Messina, Italy
2Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, Via Consolare Valeria, 98100 Messina, Italy
3Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Via Ponte don Melillo, Fisciano, 84084 Salerno, Italy

Received 7 April 2015; Revised 21 May 2015; Accepted 26 May 2015

Academic Editor: Siyaram Pandey

Copyright © 2015 Nadia Ferlazzo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [38 citations]

The following is the list of published articles that have cited the current article.

  • Angela Filocamo, Carlo Bisignano, Nadia Ferlazzo, Santa Cirmi, Giuseppina Mandalari, and Michele Navarra, “In vitro effect of bergamot (Citrus bergamia) juice against cagA-positive and-negative clinical isolates of Helicobacter pylori,” BMC Complementary and Alternative Medicine, vol. 15, no. 1, 2015. View at Publisher · View at Google Scholar
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  • Nadia Ferlazzo, Giuseppa Visalli, Santa Cirmi, Giovanni Enrico Lombardo, Pasqualina Laganà, Angela Di Pietro, and Michele Navarra, “Natural Iron Chelators: Protective Role In A549 Cells Of Flavonoids Fraction From Citrus Juices in Fe3+-Induced Oxidative Stress,” Environmental Toxicology and Pharmacology, 2016. View at Publisher · View at Google Scholar
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  • Santa Cirmi, Alessandro Maugeri, Nadia Ferlazzo, Sebastiano Gangemi, Gioacchino Calapai, Udo Schumacher, and Michele Navarra, “Anticancer Potential of Citrus Juices and Their Extracts: A Systematic Review of Both Preclinical and Clinical Studies,” Frontiers in Pharmacology, vol. 8, 2017. View at Publisher · View at Google Scholar
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  • Roberta Fusco, Santa Cirmi, Enrico Gugliandolo, Rosanna Di Paola, Salvatore Cuzzocrea, and Michele Navarra, “A flavonoid-rich extract of orange juice reduced oxidative stress in an experimental model of inflammatory bowel disease,” Journal of Functional Foods, vol. 30, pp. 168–178, 2017. View at Publisher · View at Google Scholar
  • Daniel Bedoya-Ramírez, Antonio Cilla, José Contreras-Calderón, and Amparo Alegría-Torán, “Evaluation of the antioxidant capacity, furan compounds and cytoprotective/cytotoxic effects upon Caco-2 cells of commercial Colombian coffee,” Food Chemistry, vol. 219, pp. 364–372, 2017. View at Publisher · View at Google Scholar
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  • Antonio Cilla, Maria J. Rodrigo, Lorenzo Zacarías, Begoña De Ancos, Concepción Sánchez-Moreno, Reyes Barberá, and Amparo Alegría, “Protective effect of bioaccessible fractions of citrus fruit pulps against H 2 O 2 -induced oxidative stress in Caco-2 cells,” Food Research International, 2017. View at Publisher · View at Google Scholar
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  • Eleonora Da Pozzo, Marinella De Leo, Immacolata Faraone, Luigi Milella, Chiara Cavallini, Eugenia Piragine, Lara Testai, Vincenzo Calderone, Luisa Pistelli, Alessandra Braca, and Claudia Martini, “Antioxidant and Antisenescence Effects of Bergamot Juice,” Oxidative Medicine and Cellular Longevity, vol. 2018, pp. 1–14, 2018. View at Publisher · View at Google Scholar
  • Giuseppa Visalli, Nadia Ferlazzo, Alessio Facciolà, Isa Picerno, Michele Navarra, and Angela Di Pietro, “ Ex vivo evaluation of the effects of a white grape juice extract on lymphocytic mitochondrial functions ,” Natural Product Research, pp. 1–5, 2018. View at Publisher · View at Google Scholar
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  • Laura Musumeci, Alessandro Maugeri, Santa Cirmi, Giovanni Enrico Lombardo, Caterina Russo, Sebastiano Gangemi, Gioacchino Calapai, and Michele Navarra, “ Citrus fruits and their flavonoids in inflammatory bowel disease: an overview ,” Natural Product Research, pp. 1–15, 2019. View at Publisher · View at Google Scholar
  • Daniele La Russa, Francesca Giordano, Alessandro Marrone, Maddalena Parafati, Elzbieta Janda, and Daniela Pellegrino, “Oxidative Imbalance and Kidney Damage in Cafeteria Diet-Induced Rat Model of Metabolic Syndrome: Effect of Bergamot Polyphenolic Fraction,” Antioxidants, vol. 8, no. 3, pp. 66, 2019. View at Publisher · View at Google Scholar
  • Michele Navarra, Angelo Pietro Femia, Andrea Romagnoli, Katia Tortora, Cristina Luceri, Santa Cirmi, Nadia Ferlazzo, and Giovanna Caderni, “A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apcam1137),” European Journal of Nutrition, 2019. View at Publisher · View at Google Scholar
  • Ilaria Penna, Ennio Albanesi, Rosalia Bertorelli, Tiziano Bandiera, and Debora Russo, “Cytoprotective, anti-inflammatory, and antioxidant properties of high-molecular-weight hyaluronan enriched with red orange extract in human fibroblasts exposed to ultra violet light B irradiation,” Biotechnology and Applied Biochemistry, 2019. View at Publisher · View at Google Scholar
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  • Vandana Garg, Kiran, Anju Dhiman, and Rohit Dutt, “Anticancer Potential of Functional and Medicinal Beverages,” Functional and Medicinal Beverages, pp. 199–234, 2019. View at Publisher · View at Google Scholar
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