Serum Pharmacochemistry Analysis Using UPLC-Q-TOF/MS after Oral Administration to Rats of Shenfu Decoction

Table 1

Alkaloids detected from codecoction.

Peak number	(min)	Assigned identity	Molecular formula	[M + H]^+/
				Mean measured mass (Da)	Theoretical exact mass (Da)	Mass difference (ppm)
1	4.19	Mesaconine	C24H39O9N	486.2725	486.2703	4.52
2	4.73	Carmichaeline	C22H35O4N	378.2661	378.2644	4.49
3	4.86	Cammaconine	C23H37O5N	408.2751	408.2750	0.24
4	6.39	Fuziline	C24H39O7N	454.2806	454.2805	0.22
5	6.93	Neoline	C24H39O6N	438.2863	438.2856	1.60
6	7.79	Talatizamine	C24H39O5N	422.2898	422.2906	−1.89
7	9.05	Acetyltalatizamine	C26H41O6N	464.3036	464.3012	5.17
8	9.16	10-OH-Benzoylmesaconine	C31H43O11N	606.2959	606.2914	7.42
9	10.36	Benzoylmesaconine	C31H43O10N	590.2980	590.2965	2.54
10	11.01	Benzoylaconine	C32H45O10N	604.3125	604.3122	0.50
11	11.10	Dehydrated benzoylmesaconine	C31H41O9N	572.2861	572.2860	0.17
12	11.86	10-OH-Mesaconitine	C33H45O12N	648.3018	648.3020	−0.31
13	12.36	Dehydrated benzoylhypaconine	C31H41O8N	556.2919	556.2910	1.62
14	12.70	Mesaconitine	C33H45O11N	632.3054	632.3071	−2.69
15	13.61	Hypaconitine	C33H45O10N	616.3087	616.3122	−5.68
16	14.58	Deoxyaconitine	C34H47O10N	630.3254	630.3278	−3.81