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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 980190, 19 pages
Research Article

Systems Pharmacology Dissecting Holistic Medicine for Treatment of Complex Diseases: An Example Using Cardiocerebrovascular Diseases Treated by TCM

1Evidence-Based Medicine Centre, Tianjin University of Traditional Chinese Medicine, The First Affiliated Hospital, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
2Bioinformatics Center, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi 712100, China
3School of Chemical Engineering, Dalian University of Technology, Dalian 116024, China
4State Key Laboratory of New-Tech for Chinese Medicine Pharmaceutical Process, Lianyungang, Jiangsu 22001, China

Received 10 February 2015; Revised 8 April 2015; Accepted 15 April 2015

Academic Editor: Yew-Min Tzeng

Copyright © 2015 Yonghua Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Table S1 shows the structure information of 367 compounds in Xinnaoxin Pill. Table S2 and Table S3 respectively represents the information for construction PreHIA and PreAM model. Table S4 displays the detailed information of compound-target interactions. And Table S5 shows the information of the 218 targets in this study. Figure S1 and Figure S2 reveal the workflow for PreHIA and PreAM.

  1. Supplementary Material