Research Article

Tinospora crispa Ameliorates Insulin Resistance Induced by High Fat Diet in Wistar Rats

Table 5

Effect of T. crispa on resistin, leptin, insulin, and C-peptide.

Parameter groupsResistin (ng/mL)Leptin (ng/mL)Insulin (pg/mL)C-peptide (pmol/L)

Control (NC)0.99 ± 0.1018.721 ± 2.141.59 ± 0.07161.50 ± 5.42
High fat diet (HFD)1.13 ± 0.2014.725 ± 1.112.27 ± 0.08301.66 ± 6.8
High fat diet + T. crispa (HFDTC)0.74 ± 0.20*17.428 ± 1.501.65 ± 0.07*136.48 ± 4.1*
High fat diet + orlistat (HFDO)0.84 ± 0.2022.620 ± 1.741.98 ± 0.07173.92 ± 5.11*

Means ± SEM with “*” in the same column are significant at compared to HFD group using one-way ANOVA test. = 5 rats/group.